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BNF 84 (British National Formulary) September 2022-March 2023: 84: September 2022 - March 2023

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incorporating the information into the BNF using established criteria for the presentation and inclusion of the data; . e. those published before BNF 70): Front matter, comprising information on how to use the BNF, the significant content changes in each edition, and guidance on various prescribing matters (e. Health and safety When handling chemical or biological materials particular attention should be given to the possibility of allergy, fire, explosion, radiation, or poisoning. Where the evidence base is weak, further validation may be undertaken through a process of peer review.

Cross references are included in chapter 1, where the management of diarrhoea is discussed, to the drug monograph to assist navigation. Comments from industry Close scrutiny of BNF by the manufacturers provides an additional check and allows them an opportunity to raise issues about BNF’s presentation of the role of various drugs; this is yet another check on the balance of BNF’s advice. Cautionary and advisory labels that pharmacists are recommended to add when dispensing are included in the medicinal forms section.It is not possible to keep abreast of all of the generic products available on the UK market, and so this information serves as a reminder to the healthcare professional that, if the presence of a particular excipient is of concern, they should check the product literature for the particular product being prescribed or dispensed. Drug monographs have also changed structurally: additional sections have been added, ensuring greater regularity around where information is located within the publication. In addition, BNF content can be integrated into a local formulary by using BNF on FormularyComplete; see www. Use of this resource throughout the health service helps to ensure that medicines are used safely, effectively, and appropriately. Extemporaneous preparation A product should be dispensed extemporaneously only when no product with a marketing authorisation is available.

Grade B: Moderate strength Guidelines, assessed using AGREE II, that meet the grade B threshold; or a body of evidence including studies rated as 2++, directly applicable to the target population, and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 1++ or 1+.This is most common for drugs formulated in combinations, where users will be signposted to the monographs for the individual ingredients (e. For legal requirements relating to prescriptions of Controlled Drugs, see Controlled drugs and drug dependence p. Safety monitoring Biosimilar medicines are subject to a black triangle status (A) at the time of initial authorisation. EEA and Swiss prescriptions Pharmacists can dispense prescriptions issued by doctors, dentists, and nurse prescribers from the European Economic Area (EEA) or Switzerland (except prescriptions for controlled drugs in Schedules 1, 2, or 3, or for drugs without a UK marketing authorisation). Read more about the condition New: A new, unread, unused book in perfect condition with no missing or damaged pages.

In addition, general advice relevant to other routes of administration is provided within this section (e. Grade A: High strength NICE-accredited guidelines; or other guidelines, assessed using AGREE II, that meet the grade A threshold; or at least one meta-analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or a body of evidence consisting principally of studies rated as 1+, directly applicable to the target population, and demonstrating overall consistency of results. Monograph titles follow the convention of recommended international non-proprietary names (rINNs), or, in the absence of a rINN, British Approved Names. The more important changes are listed under Changes; changes listed online are cumulative (from one print edition to the next), and can be printed off each month to show the main changes since the last print edition as an aide memoire for those using print copies. Doses for children can be identified by the relevant age range and may vary according to their age or body-weight.Where an unlicensed drug is included in the BNF, this is indicated in the unlicensed use section of the drug monograph. Correspondents in the pharmaceutical industry have provided information on new products and commented on products in the BNF. Now, all of the information for the systemic use of a drug is contained within one monograph, so codeine phosphate p. The recommendation is given a grade that is extrapolated from the level of evidence, and an assessment of the body of evidence and its applicability. g. asthma), followed by the monographs of the drugs used to manage the conditions discussed in the treatment summary.

As with earlier editions of the BNF, practitioners must ensure that the particular product being prescribed or dispensed is appropriate. This will enable any suitable product to be dispensed, thereby saving delay to the patient and sometimes expense to the health service. Once on a page, visual cues aid navigation: treatment summary information is in black type, with therapeutic use titles similarly styled in black, whereas the use of colour indicates drug-related information, including drug classification titles, drug class monographs, and drug monographs.It is important to report suspected adverse reactions using the Yellow Card Scheme (see Adverse reactions to drugs p. Patients should be prescribed a preparation that complements their daily routine, and that provides the right dose of drug for the right indication and route of administration. Although navigation is possible by browsing, primarily access to the information is via the index, which covers the titles of drug class monographs, drug monographs, and treatment summaries. This does not apply to items directed to be used as required—if the dose and frequency are not given then the quantity to be supplied needs to be stated. The Dental Advisory Group oversees the preparation of advice on the drug management of dental and oral conditions; the Group includes representatives of the British Dental Association and a representative from the UK Health Departments.

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